个人情况介绍、概览
兰丽丽,女,博士,特聘副教授。2017年毕业于黑龙江中医药大学,获制药工程学士学位,2020年获沈阳药科大学药物分析学硕士学位,2023年于同校获药物分析学博士学位。同年被聘为沈阳药科大学特聘副教授,现为分析化学教研室专任教师。作为课题负责人主持了国家自然科学基金青年基金项目1项,辽宁省基本科研项目1项。目前已在Food Chemistry, Phytomedicine, Ethnopharmacology, Journal of Chromatography A, Journal of Pharmaceutical and Biomedical Analysis等期刊发表论文10余篇。
人才称号、社会兼职等(限填10项)
1.沈阳市D类人才;
2.《药学研究》青年编委;
3.《中南药学》青年编委;
主要研究方向(限填3项)
研究方向一:中药定量指纹学理论和评价方法研究
研究方向二:中药质量控制与作用机制研究
主持、参与的科研项目(含科研获奖等情况)(限填10项)
1.基于系统指纹定量法的多维指纹整合分析辅助栀子金花丸抗抑郁药效物质基础与作用机制研究,国家自然科学基金项目,基金编号82404858(负责人)
2.“色-光-热”多维指纹图谱整合分析辅助栀子金花丸抗抑郁药效物质基础与作用机制研究,辽宁省教育厅基本科研项目,基金编号LJ212410163028(负责人)
近年来发表代表性论文(限第一作者或通讯作者,SCI须写明影响因子):(限填10篇)
[1] T. Yang, X. Liu, L. Xue, X. Liu, L. Zhang, L. Lan*, H. Zhang*, G. Sun*, Quality assessment of Red Yeast Rice by fingerprint and fingerprint-effect relationship combined with antioxidant activity, Food Chemistry, 438 (2024) 137744. (IF: 8.8)
[2] Mingjia Liu, Lili Lan*, Gang Li *, Guoxiang Sun*, Multi-dimensional profiles combined with antioxidant activity and fingerprint-efficacy relationship to analyze the quality of Astragali Radix from different sources Food Chemistry, 461 (2024) 140848. (IF: 8.8)
[3] J. Fan, X. Wang, Q. Chang, G. Sun*, L. Lan*, Evaluating the quality consistency of antiviral oral liquid by highperformance liquid chromatography five-wavelength matched average fusion fingerprint combined with electrochemical fingerprint and ultraviolet spectral quantum fingerprint, Journal of Chromatography A, 1702 (2023) 464098. (IF: 4.1)
[4] P. Wang, X. Wang, Y. Li, R. He, J. Gao, C. Chen, H. Dai, Z. Cao, L. Lan*, G. Sun*, W. Sun*, Thorough evaluation of the Chinese medicine preparations and intermediates using high performance liquid chromatography fingerprints and ultraviolet quantum fingerprints along with antioxidant activity: Shuanghuanglian oral solution as an example, Journal of Chromatography A, 1705 (2023) 464196. (IF:4.1)
[5] L. Lan, T. Yang, J. Fan, G. Sun, H. Zhang, Anti-inflammation activity of Zhizi Jinhua Pills and overall quality consistency evaluation based on integrated HPLC, DSC and electrochemistry fingerprints, Journal of Ethnopharmacology, 311 (2023) 116442. (IF: 5.4)
[6] L. Lan, J. Zhang, T. Yang, D. Gong, Z. Zheng, G. Sun, P. Guo, H. Zhang, Compound synthesizing profiling based on quantitative HPLC fingerprints combined with antioxidant activity analysis for Zhizi Jinhua pills, Phytomedicine, 105 (2022) 154340. (IF: 7.9)
[7] L. Lan, W. Sun, Q. Chang, G. Sun, Comprehensive evaluation of Licorice extract by five-dimensional quantitative profiling, Journal of Chromatography A, 1644 (2021) 462105. (IF: 4.6)
[8] L. Lan, Y. Zhang, M. Zhang, G. Sun, Evaluation of the quality of compound liquorice tablets by DSC and HPLC fingerprints assisted with dissolution, Journal of Pharmaceutical and Biomedical Analysis, 175 (2019) 112715. (IF: 3.2)
专利及其他(限填10项)
1.孙国祥,兰丽丽,孙万阳,张晶,巩丹丹,陈金玉,王刚.栀子金花丸(水丸)标准制剂模式的标准指纹图谱和质量一致性评价方法.202110204451 .7