个人情况介绍、概览
董舒卉,女,博士,特聘副教授。2018年毕业于沈阳药科大学,获药学学士学位。同年考入沈阳药科大学中药学院天然药物化学专业攻读硕士学位。2020年通过硕博连读考核继续攻读博士学位,并于2023年12月获得天然药物化学博士学位。毕业后留校任教,2024年12月被聘为沈阳药科大学特聘副教授。作为课题负责人主持国家自然科学基金青年基金项目1项,辽宁省教育厅项目1项。目前以第一作者身份在Trends in Analytical Chemistry, Organic Chemistry Frontiers, Bioorganic Chemistry, Chinese Journal of Chemistry等期刊发表论文十余篇。
人才称号、社会兼职等(限填10项)
1.《陕西中医药大学学报》《现代中医药》青年编委;
2.《Food & Medicine Homology》青年编委;
3.世界中医药学会联合会中药化学专业委员会委员;
4.中华中医药学会中药化学分会第五届委员会青年委员
主要研究方向(限填3项)
研究方向一:活性天然产物的精准导向分离
研究方向二:基于计算化学及人工智能的复杂天然产物结构确证/修正
研究方向三:活性天然产物的剂型设计
主持、参与的科研项目(含科研获奖等情况)(限填10项)
1. 两种雷公藤属植物中倍半萜吡啶生物碱类成分的靶向分离及其银屑病治疗活性研究,国家自然科学基金青年科学基金项目,基金编号32400328(负责人)
2. 雷公藤属药用植物特征性成分的靶向分离及其银屑病治疗活性研究,辽宁省教育厅项目,基金编号LT212410163054(负责人)
3. Elephantopinolide A-P, germacrane-type sesquiterpene lactones from Elephantopus scaber induce apoptosis, autophagy and G2/M phase arrest in hepatocellular carcinoma cells,2024年,沈阳市自然科学学术成果三等奖(排名第二)
近年来发表代表性论文(限第一作者或通讯作者,SCI须写明影响因子):(限填10篇)
1. Shu-Hui Dong; Zhi-Kang Duan, Ming Bai, Xiao-Xiao Huang, Shao-Jiang Song. Advanced technologies targeting isolation and characterization of natural products, Trends in Analytical Chemistry, DOI: 10.1016/j.trac.2024.117711. (IF=11.8)
2. Shu-Hui Dong; Jin-Ling Han, Xin-Yu Chang, Mei-Ya Lian, Xin Zhang, Xiao-Ling Liu, Ming Bai, Xiao-Xiao Huang, Shao-Jiang Song, Rapid screening of unprecedented sesquiterpenes with distinctive ring skeletons from Daphne aurantiaca employing an integrated strategy, Organic Chemistry Frontiers, DOI: 10.1039/d3qo00902e. (IF=4.6)
3. Shu-Hui Dong; Zhi-Kang Duan, Yun-Fei Ai, Xiao-Fang Zhou, Xin Zhang, Mei-Ya Lian, Xiao-Xiao Huang, Ming Bai, Shao-Jiang Song, Guaiane-type sesquiterpenoids with various ring skeletons from Daphne bholua uncovered by molecular networking and structural revisions of previously reported analogues, Bioorganic Chemistry, DOI: 10.1016/j.bioorg.2022.106208. (IF=5.1)
4. Chun-Xin Zou1, Shu-Hui Dong1, Zi-Lin Hou, Guo-Dong Yao, Bin Lin, Xiao-Xiao Huang, Shao-Jiang Song, Modified lanostane-type triterpenoids with neuroprotective effects from the fungus Inonotus obliquus, Bioorganic Chemistry, DOI: 10.1016/j.bioorg.2020.104438. (IF=5.275)
5. Shu-Hui Dong, Bin Lin, Xiao-Bian Xue, Ming Bai, Xiao-Xiao Huang, Shao-Jiang Song, Discovery of β-dihydroagarofuran-type sesquiterpenoids from the leaves of Tripterygium wilfordii with neuroprotective activities, Chinese Journal of Chemistry, DOI: 10.1002/cjoc.202000471. (IF=5.560)
6. Shu-Hui Dong, Mei-Ya Lian, Jin-Ling Han, Yun-Fei Ai, Xiao-Fang Zhou, Ming Bai, Xiao-Xiao Huang, Shao-Jiang Song, Rapid screening of diarylpentanoids from Daphne bholua, Phytochemistry, DOI: 10.1016/j.phytochem.2023.113614. (IF=3.2)
7. Mei-Ya Lian1, Shu-Hui Dong1, Yun-Fei Ai, Zhi-Kang Duan, Ming Bai, Xiao-Xiao Huang, Shao-Jiang Song, Eight structurally diverse components with anti-acetylcholinesterase activity from Daphne bholua, Phytochemistry, DOI: 10.1016/j.phytochem.2024.114015. (IF=3.2)
8. Jia-Yi Li1, Shu-Hui Dong1, Xin Zhang, Zi-Jian Liu, Jin-Le Hao, Bin Lin, Ming Bai, Xiao-Xiao Huang, Shao-Jiang Song, Structurally diverse terpenoids from Elephantopus scaber L. and their acetylcholinesterase inhibitory activities, Phytochemistry, DOI: 10.1016/j.phytochem.2023.113892. (IF=3.2)
9. Shu-Hui Dong, Ming Bai, Zi-Lin Hou, Wei-Yu Zhou, Guo-Dong Yao, Bin Lin, Xiao-Xiao Huang, Shao-Jiang Song. Dihydroagarofuran sesquiterpenoid derivatives from the leaves of Tripterygium wilfordii with potential neuroprotective effects against H2O2-induced SH-SY5Y cell injuries, DOI: 10.1039/d0nj00703j. (IF=3.591)
10. Yun-Fei Ai1, Shu-Hui Dong1, Bin Lin, Xiao-Xiao Huang, Shao-Jiang Song, Acylated sucroses and butenolide analog from the leaves of Tripterygium wilfordii Hook. f. and their potential anti-tyrosinase effects, DOI: 10.1016/j.fitote.2022.105250. (IF=3.4)
专利及其他(限填10项)
1. 宋少江,黄肖霄,董舒卉,何青军,周乐,白明,二氢沉香呋喃倍半萜及医药用途. 专利号: 201910686810.X.
2. 宋少江,黄肖霄,董舒卉,连美雅,藏东瑞香中的愈创木烷型倍半萜类化合物及其制备方法和应用. 专利号: 202211171694.6.
3. 宋少江,黄肖霄,董舒卉,连美雅,藏东瑞香中的二芳基戊烷类化合物及其制备方法和应用. 专利号: 202211463128.2.
4. 宋少江,黄肖霄,董舒卉,连美雅,橙花瑞香中新骨架愈创木烷倍半萜及其制备方法和应用. 专利号: 2023102551510.