个人情况介绍、概览

秦峰，沈阳药科大学副教授，硕士生导师，药物分析学博士。主要研究方向为生物样品分析、药物动力学和药物代谢、中药药效物质基础和药物质量标准等方面的研究；在多组分成分及复杂基质样品分析方法的建立，应用HPLC、HPLC/MS/MS、UHPLC/MS/MS等分离分析技术进行定性、定量分析方面具有较丰富的经验。主持或参加多项国家自然科学基金项目、国家科技重大专项、教育部博士学科点专项科研基金，还参与过多项人体药物动力学、生物利用度和生物等效性研究课题。目前已在Analytical and Bioanalytical Chemistry, Microchemical Journal, Journal of Pharmaceutical and Biomedical Analysis, Journal of Chromatography B, Biomedical chromatography, Chirality, Journal of Colloid and Interface Science, 药物分析和药学学报等期刊发表论文60余篇，其中SCI收载40余篇，其中以第一作者或者通讯作者发表27篇。担任Asian Journal of Pharmaceutical Sciences、Microchemical Journal、Journal of Pharmaceutical and Biomedical Analysis、Journal of Chromatography B、Biomedical chromatography等杂志审稿人，中国药理学会药物代谢专业委员会青年委员会委员；多次获得辽宁省自然科学学术成果奖。也是国家精品课程-分析化学授课成员之一及辽宁省教学团队成员之一。

人才称号、社会兼职等

担任Asian Journal of Pharmaceutical Sciences、Microchemical Journal、Journal of Pharmaceutical and Biomedical Analysis、Journal of Chromatography B、Biomedical chromatography等杂志审稿人，中国药理学会药物代谢专业委员会青年委员会委员

主要研究方向

研究方向一：体内药物分析（生物样品分析）

研究方向二：药物动力学和药物代谢研究

研究方向三：中药药效物质基础和药物质量标准等方面的研究

主持、参与的科研项目（含科研获奖等情况）

主持承担国家自然科学基金课题一项（川丁特罗潜在活性及毒性代谢及其相关酶学研究，编号-81102505），参加国家自然科学基金项目四项（骨碎补补肾壮骨药效物质基础的代谢组学研究，编号-20705021；脂质体电动色谱与药物吸收和分布的关系，编号-30801443；克服肿瘤渗透限制的多阶段纳米载体系统的研究，编号-81273450；基于多组学和质谱成像技术构建骨疏丹调控“肠-肾-骨轴”的精准代谢网络，编号-82174235），国家科技重大专项课题子课题三项（骨碎补补肾壮骨药效物质基础的代谢组学研究；抗骨质疏松药物骨疏丹研究；左旋川丁特罗的研究和开发），教育部博士点基金项目一项（抗Ⅱ型糖尿病药物作用机制的代谢组学研究），其他辽宁省和沈阳市课题三项，还主导过多项人体药物动力学、生物利用度和生物等效性研究课题。

近年来发表代表性论文(限第一作者或通讯作者，SCI须写明影响因子)：

1. Yihong Jiang#, Yaling Niu#, Congchao Ning, Feng Qin*, Chengda Yan*, Xiumei Lu*. A simple, rapid and sensitive method for the determination of bisoprolol in human plasma by ultra performance liquid chromatography-tandem mass spectrometry. Biomedical Chromatography(2025), doi.org/10.1002/bmc.70054.（SCI IF 1.911/4区）共同通讯作者

2. Yuting Wang, Yuequan Wang, Yuting Liu, Mingyang Zhou, Xianbao Shi, Xiaohui Pu, Zhonggui He*, Shenwu Zhang*, Feng Qin*, Cong Luo*. Small molecule–engineered nanoassembly for lipid peroxidation–amplified photodynamic therapy. Drug Delivery and Translational Research, https://doi.org/10.1007/s13346-023-01490-w （SCI IF 5.4/1区）共同通讯作者

3. Xihong Zhao#, Chunjing Lv1#, Hong Chen, Feng Qin*, Xiumei Lu*. Determination of flurbiprofen in rat plasma using ultra-high performance liquid chromatography–tandem mass spectrometry and its application in a pharmacokinetic study. Biomedical Chromatography(2023), doi.org/10.1002/bmc.5780, 2023;e5780.（SCI IF 1.911/4区）共同通讯作者

4. Yue Yuan, Chengze Zhu, Jiayi Zhang, Qian Hang, Huawen Yin, Longshan Zhao, Zhili Xiong*, Feng Qin*. Polydopamine- and MOFs-based molecularly imprinted microfiltration membranes in syringe filter for selective capture of thiamphenicol, florfenicol and chloramphenicol in milk samples. Microchemical Journal 193 (2023) 109009.排名8/8（SCI IF 4.8/1区）共同通讯作者

5. Qikun Jiang, Sirun Lu, Xiaolan Xu, Chenxia Bai, Qing Yan, Mengna Fang, Li Huang,Chunming Jin, Yunran Zhang, Jin Sun, Zhonggui He, Chunyang Zhao, Feng Qin*, Yongjun Wang*, Tianhong Zhang*. Inhibition of alanine-serine-cysteine transporter 2-mediated auto-enhanced photodynamic cancer therapy of co-nanoassembly between V-9302 and photosensitizer. Journal of Colloid and Interface Science 629 (2023) 773–784. 排名13/15（SCI IF 9.9/1区）共同通讯作者.

6. Siyao Zhang, Shutong Chen, Yujing Song, Ying Xin, Ying Cui, Feng Qin*. Determination of meloxicam in human plasma by ultra high performance liquid chromatography-tandem mass spectrometry and its application in a pharmacokinetic study. Biomedical Chromatography(2022), 10.1002/bmc.5395.（SCI IF 1.911/4区）排名5/6.通讯作者.

7. Xiaoming Zhu, Shuwen Geng, Tao Wen, Feng Qin*, Longshan Zhao*. Vortex-assisted natural deep eutectic solvent dispersive liquid–liquid microextraction based on the solidification of a floating organic drop for the determination of benzoic acid and sorbic acid in condiments. Anal Methods (2021), 13(40): 4805-4813.（SCI IF 3.532/1区）排名4/5.共同通讯作者.

8. Bian Yuwei., Wang Yu., Yu Jiaping., Zheng Shuwen., Qin Feng*., Zhao Longshan*. Analysis of six preservatives in beverages using hydrophilic deep eutectic solvent as disperser in dispersive liquid-liquid microextraction based on the solidification of floating organic droplet. J Pharm Biomed Anal, 2021, 195: 113889. doi:10.1016/j.jpba.2021.113889. （SCI IF 3.935/3区）排名5/6.共同通讯作者

9. Yuan Yunxia., Wu Qiong., Zhao Jing., Feng Zhiao., Dong Jiani., An Ming., Wu Guodong., Qin Feng*., Zhao Longshan*. Investigation of pathogenesis and therapeutic targets of acute myeloid leukemia based on untargeted plasma metabolomics and network pharmacology approach. J Pharm Biomed Anal, 2021, 195: 113824. doi:10.1016/j.jpba.2020.113824. Epub 2020 Dec 9. （SCI IF 3.935/3区）排名8/9.共同通讯作者.

10. Yang Zixin., Zhao Jiaxing., Feng Yao., Lei Yu., Liu Dan., Qin Feng*., Zheng Jiang*., Wang Shaojie*. Identification, synthesis and structural confirmation of process-related impurities in proparacaine hydrochloride. J Pharm Biomed Anal, 2020, 190: 113497. doi:10.1016/j.jpba.2020.113497. （SCI IF 3.935/3区）排名6/8.共同通讯作者.