导师介绍
颜廷旭
导师姓名: 颜廷旭
性别:
出生年月: 198410
所在学院: 功能食品与葡萄酒学院
所在部门: 食品质量与安全教研室
职称: 副教授
职务:
最高学位: 博士
所招专业: 1008中药学(硕士)、1056中药学(硕士)
通讯地址: 辽宁省本溪高新技术产业开发区华佗大街26号
办公电话: 024-43580305
手机号码:
E-mail: yantingxu@126.com
导师类别: 硕士生导师
导师介绍

个人情况介绍、概览

颜廷旭,博士,副教授,硕士生导师,作为课题负责人主持国家自然科学基金面上项目1项,中国博士后科学基金面上资助项目1项,辽宁省科技厅博士启动项目1项,辽宁省教育厅面上项目1项,江苏省博士后科研资助计划项目1项,沈阳药科大学博士启动基金1项,沈阳药科大学国自然培育基金1项等。相关科研成果已发表SCI论文50余篇,并于2020年获沈阳市自然学术成果三等奖。

人才称号社会兼职

1.辽宁省“兴辽英才计划”青年拔尖人才;

2.国家自然科学基金函审评议专家

3.沈阳市高级人才

4.儿童成长与特殊食品专业委员会常委

5.辽宁省食品科学技术学会青年委员

6.Journal of Polyphenols杂志编委;

主要研究方向

研究方向一:神经退行性疾病的中药干预

研究方向二:功能食品功效因子筛选与评价

研究方向三:新功能食品开发

主持、参与的科研项目(含科研获奖等情况)

1.五味子调控机体内源性大麻素系统参与“肠脑对话”的抗抑郁物质基础与作用机制研究,国家自然科学基金面上项目,82173961,负责人;

2.五味子总木脂素重塑机体氮平衡整体调节肠-肝-脑轴多靶点协同抗抑郁作用机制研究,中国博士后科学基金第68批面上资助,2020M681518,负责人;

3.基于肠道菌群介导的五味子抗抑郁作用机制研究,辽宁省博士科研启动基金计划项目,2019-BS-233,负责人;

4.五味子总木脂素重塑机体氮平衡抗抑郁作用机制研究,辽宁省教育厅面上项目,LJKZ0950,负责人;

5.大株红景天胶囊调控线粒体自噬改善MIRI作用机制研究,江苏省博士后科研资助计划资助,2020Z149,负责人

6.2018年沈阳市自然科学学术成果奖(学术论文类)三等奖(排名第一)

近年来发表代表性论文(限第一作者或通讯作者,SCI须写明影响因子)

1.Xiaoying Zhang, Shiyu Wang, Yanjun Jin, Jinyu Wang, Ruixuan Wang, Xihan Yang, Shuanglin Zhang,Tingxu Yan*, and Ying Jia*,Wei-Tong-Xin ameliorated cisplatin-induced mitophagy and apoptosis in gastric antral mucosa by activating the Nrf2/HO-1 pathway. Journal of Ethnopharmacology. 2023, 308: 116253.中科院1区IF:5.4

2.Fei Lin, Guanglin Zhang, Xihan Yang, Mengshi Wang, Ruixuan Wang, Meiqi Wan, Jinyu Wang, Bo Wu,Tingxu Yan*, and Ying Jia*, A network pharmacology approach and experimental validation to investigate the anticancer mechanism and potential active targets of ethanol extract of Wei-Tong-Xin against colorectal cancer through induction of apoptosis via PI3K/AKT signaling pathway, Journal of Ethnopharmacology, 2023, 303: 115933,中科院1区IF:5.4

3.Mengjie Xu, Yunfang Yang, Jing Peng, Yue Zhang, Bo Wu, Bosai He, Ying Jia*,Tingxu Yan*, Effects of Alpinae Oxyphyllae Fructus on microglial polarization in a LPS-induced BV2 cells model of neuroinflammation via TREM2, Journal of Ethnopharmacology, 2023, 302: 115914.中科院1区IF:5.4

4.Tingxu Yan, Xu Li, Xin Wang, Yue Zhang, Bosai He, Ying Jia*, Wei Xiao*. Rhodiola wallichiana var.cholaensis protects against myocardial ischemia-reperfusion injury by attenuating oxidative stress-mediated apoptosis via enhancing Nrf2 signaling. International Journal of Cardiology. 2023, 384: 62-73.中科院2区IF:3.5

5.Jinyu Wang, Guanglin Zhang, Yunfang Yang, Xiaoying Zhang, Kaifang Shi, Xiaozhuo Zhang,Tingxu Yan*, and Ying Jia*,Schisandra chinensis Lignans Exert Antidepressant Effects by Promoting BV2 Microglia Polarization toward the M2 Phenotype through the Activation of the Cannabinoid Receptor Type-2–Signal Transducer and Activator of Transcription 6 Pathway. Journal of Agricultural and Food Chemistry, 2022 , 70: 14157−14169中科院1区IF:6.1

6.Wenjuan Liu, Xiaoying Zhang, Tiancheng Ma, Jinyu Wang, Xinyan Lv, Bo Wu,Tingxu Yan*, Ying Jia*. Uncovering the pharmacological mechanism of Wei-Tong-Xin against gastric ulcer based on network pharmacology combined with in vivo experiment validation. Journal of Ethnopharmacology. 2022; 293: 115282.中科院1区IF:5.4

7.Tingxu Yan, Qianqian Mao, Xiaozhuo Zhang, Bo Wu, Kaishun Bi, Bosai He and Ying Jia. Schisandra chinensis protects against dopaminergic neuronal oxidative stress, neuroinflammation and apoptosis via the BDNF/Nrf2/NF-κB pathway in 6-OHDA-induced Parkinson’s disease mice. Food & Function, 2021, 12: 4079-4091.中科院1区IF:6.317

8.Tingxu Yan, Nizhi Wang, Bing Liu, Bo Wu, Feng Xiao, Bosai He, Ying Jia*. Schisandra chinensis ameliorates depressive-like behaviors by regulating microbiota-gut-brain axis via its anti-inflammation activity. Phytotherapy Research. 2021, 35: 289-296.中科院2区,IF: 6.388

9.Mengjie Xu#,Tingxu Yan#, Guowei Gong, Bo Wu, Bosai He, Yiyang Du, Feng Xiao*, Ying Jia*. Purification, structural characterization, and cognitive improvement activity of a polysaccharides from Schisandra chinensis. International Journal of Biological Macromolecules, 2020, 163: 497-507.中科院1区,IF:6.953

10.Tingxu Yan, Tingting Nian, Zhengzheng Liao, Feng Xiao, Bo Wu, Kaishun Bi, Bosai He, and Ying Jia*. Antidepressant effects of a polysaccharide from okra (Abelmoschus esculentus (L) Moench) by anti-inflammation and rebalancing the gut microbiota. International Journal of Biological Macromolecules. 2020, 144:427-440中科院1区,IF:6.953