个人简介

许永男，博士，教授。1984年毕业于吉林大学化学系，获理学学士学位。于2000年和2003年分别获得韩国首尔国立大学天然物科学研究所（药学院）天然物科学专业理学硕士和博士学位。

主要从事本科生药学（英语强化）专业《有机化学》（双语）和硕士研究生《近代有机合成基础》（双语）教学。

主要研究方向为活性天然产物的分离、合成及以此为先导化合物的新药研发。

近年来发表论文50余篇，其中SCI收录30余篇。获得中国专利许可4项。

1.Bach DH, Liu JY, Kim WK, Hong JY, Park SH, KimDH, Qin SN, Luu TTT, Park HJ, Xu YN*, Lee SK*, Synthesis and biological activity of new phthalimides as potential anti-inflammatoryagents. Bioorganic & MedicinalChemistry, 25 (13), 3396-3405 (2017)

2.Fan YH, Liu JY, Liu D, Bao Y, Wang J, Zhao QC*, Xu YN*, NSCA-1—a novel N-substituted coumalamidederivative—increases Adriamycin sensitivity in HepG2/adriamycin cells throughmodulating Akt/GSK-3 signaling and p53-depnedant apoptotic pathway. Environmental Toxicology and Pharmacology,49 (1), 1-7 (2017)

3.Wang WZ, Yuan J, Fu XL,Meng FC, Zhang SJ, Xu WR, Xu YN*,Huang CJ*, Novel anthranilamid-based Fxa inhibitors: drug desing, synthesis andbiological evaluation. Molecules,21, 491-506 (2016)

4.Fan YH, Lu HY, Ma HD, Feng F, Hu XL, Zhang Q,Wang J,Xu YN*, Zhao QC*, Bioactive compounds of Eriocaulonsieboldianum blocking proliferation and inducing apoptosis of HepG2 cellsmight be involved in Aurora kinase inhibition. Food & Function, 6(12), 2746-3759 (2015)

5.Lv WW, Qin SN, Chen CQ, Zhang JJ, Xu YN*, Zhao QC*, Isoindolone derivative QSN-10c induces leukemic cellapoptosis and suppresses angiogenesis via PI3K/AKT signaling pathway inhibition. Acta Pharmacologica Sinica, 35 (5), 625-635 (2014).

6.秦思凝，吕文文，王铨，赵庆春，许永男*，N-取代邻苯二甲酰亚胺类衍生物的设计与合成及活性评价。高等学校化学学报，34 (12),1745-2751 (2013).

7.Gong YX,  Hua HM, Xu YN*, Liu JY, Yu ZG, Ma J, ZhangH, Jing YK, Triterpene Saponins from Clematismandshurica and Their Antiproliferative Activity. Planta Medica, 79 (11), 987-994 (2013).

8. Chen T,Zheng Y, Xu ZC*, Zhao M, Xu YN*, Cui JN*, A red emissionfluorescent probe for hydrogen sulfide and its application in living cellsimaging. Tetrahedron Letters, 54(23), 2980-2982 (2013).

　　现任《中国药物化学杂志》编委，“世界中医药学会联合会”中药化学专业委员会理事，“辽宁省民族科普协会”理事长，“中国朝鲜族科技工作者协会”副理事长，中国民主同盟沈阳市科技委员会委员等职。